Other uses for this medicine
Leucovorin is also used in combination with the chemotherapy 5-fluorouracil in treating colon cancer. In this case, folinic acid is not used for "rescue" purposes. Rather, folinic acid enhances the effect of 5-fluorouracil on inhibiting thymidylate synthase.
Leucovorin is also sometimes used to prevent toxic effects of high doses of antimicrobial dihydrofolate reductase inhibitors such as trimethoprim and pyrimethamine.
Why is this medication prescribed?
Dosage and using this medicine
What special precautions should I follow?
What should I do if I forget a dose?
What side effects can this medication cause?